Post frame construction utilizes a variety of materials designed to ensure durability, efficiency, and aesthetic appeal. The primary structural components are large posts or poles, typically made from treated wood, which provide the foundational support for the building.

These posts are secured deep into the ground or set on concrete piers, creating a stable base for the structure. The framework is then built out with horizontal girts (also wood) and roof trusses, which can be made from wood or engineered wood products. The choice of wood treatment is critical for the longevity of the posts, with options designed to resist decay, moisture, and insect damage.

For the building's exterior, a range of materials can be used depending on the desired look and functionality. Metal panels are a popular choice for roofing and siding due to their durability, low maintenance, and quick installation. However, other materials like vinyl siding, wood siding, brick veneer, or composite materials are also common for both aesthetic and functional purposes.

The roof can be covered with metal roofing, asphalt shingles, or other materials suited to the building's design and the local climate. Insulation is another crucial component, with options including fiberglass batts, spray foam, or rigid foam boards to enhance the building's energy efficiency.

Finally, doors and windows complete the structure, with choices ranging from standard residential styles to commercial-grade options designed for durability and security.